a: avastin mechanism ~
b: damming a river
What:
"Think of it like damming a river. Bevacizumab can block the main flow, but then once a tumor's need builds up behind this dam, water starts to flow around the blockage in the form of streams and tributaries. That's like these other growth factors -- eventually a tumor becomes able to use these tributaries of VEGF-C, VEGF-D and placental growth factor to supply itself with the 'water' it needs "
Useful?
Writer: Christopher Lieu, MD
LCC:
Where:
Date: Jan 9 2014 7:54 PM
# 4641 Critique Analogy