dna

What: "DNA is like a twisted ladder, where the sugar and phosphate are the rails, and the base pairs are the rungs. The rails run in opposite orientation to each other."

Writer: James Watson

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Where:

Date: Sep 21 2011 9:03 PM

What: "DNA is like your phone line. As Northwestern University biophysicist Johnathan Widom put it in a talk recently, DNA simultaneously encodes multiple overlapping signals, just like your phone line that allows you to call home while you're surfing the net via DSL."

Writer: Johnathan Widom

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Where:

Date: Sep 21 2011 9:05 PM

What: "I started thinking, The kind of deformations that happen to underwater cables are the same that occur in DNA molecules"

Writer: Sachin Goyal

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Date: Sep 21 2011 9:08 PM

What: "DNA is like a spiral staircase, with each step of the staircase rising 0.34 nanometers and turning 36 degrees. Once you know how to build a single step and how each step connects to the next, you can build a molecule model of any length by just stacking copies of the step."

Writer: ernie wright

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Where: Reference Link Has Evaporated

Date: Sep 21 2011 9:10 PM

What: "DNA is like a book which is made up out of four letters: Adenine, Guanine, Cytosine, and Thymine (A C G T) that appear in a certain sequence.One chromosome is like a sentence, much of it doesn't make any sense to us: the letters seem to be in a random order. But sometimes the letter DO make sense, that is a gene, like a word."

Writer: Monique

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Date: Sep 21 2011 9:13 PM

What: "DNA is inter-dimensional. It is both physical and non physical. In fact, much more of our DNA is non physical than is physical in nature. DNA is like a group of cards all picked and assembled by Source creating the physical concept of you. And it is now your choice from your separate physical life, how to play those cards with your own free will."

Writer: Teal Scott

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Date: Sep 21 2011 9:15 PM

What: "DNA is the archival record of our being. It's carried in every cell of our body. RNA is the working copy of that record. DNA is like the American constitution buried in a Washington vault. RNA is like the working law. It's fractional and varied, but it always reflects that document in the vault."

Writer: John H. Lienhard

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Date: Sep 21 2011 9:26 PM

What: "Put simply, DNA is like a very long open necklace of many millions of colored beads; actually, billions of colored beads. The colors can be in any order along the length of the necklace and the order of these colored beads is unique to an individual and determines the individual's characteristics."

Writer: Hershell Goldman

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Date: Sep 21 2011 9:31 PM

What: "The most common metaphor for DNA is a blueprint, the belief being that all of the information required for an organism lay within its DNA and simply waits to be unlocked. It codes for the designers and workers, as well as how to combine the construction materials."

Writer: Randall Willis

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Date: May 22 2013 6:29 PM

What: "I'd say DNA is like some priest who long ago usurped the the Book of Life, from RNA, but RNA *wrote* the book originally, and still fills far more essential functions than DNA does. DNA just sits in its nucleus and "reflects". A cell lives MUCH longer if you block its DNA function than if you block its RNA functions (and that's no guess: we have chemicals that can selectively block either one)"

Writer: Orpheus

LCC:

Where: Reference Link Has Evaporated

Date: Oct 25 2013 6:51 PM

What:

"DNA is not like C source but more like byte-compiled code for a virtual machine called 'the nucleus'. It is very doubtful that there is a source to this byte compilation - what you see is all you get. "

Writer: bert hubert

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Date: Apr 29 2014 6:39 PM

What: "cDNA is like the DNA that originally produced the mRNA except that it contains no introns." On page 334 of the linked book.

Writer: Richard E. Neapolita

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Date: May 2 2013 1:02 PM

What: "OUR D.N.A IS LIKE A RECEIVER COIL FROM THE UNIVERSE TO GIVE EACH OF US UNLIMITED LOVE ENERGY IF ONLY WE LET IT"

Writer: Not Stated

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Date: Sep 21 2011 9:20 PM

What: "Ligase is like a molecular stitcher. .... If there is break in a double stranded DNA, they ligate the broken ends by phosphodiester bond formation between the broken ends" by someone at Davidson College.

Writer: Not Stated

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Date: Mar 10 2013 10:14 AM

What: DNA ligase is an enzyme. Enzymes, biological catalysts, generally perform 2 functions. They provide an ideal spatial orientation for 2 or more molecules to react. Once said molecules are aligned correctly, the enzyme reversibly interacts with the molecules to lower the transition energy for that particular reaction. So, a valid association for DNA ligase is a sewing machine. A sewing machine can do 2 things; it can provide a surface for cloth to be aligned correctly, and it provides the means for the 2 separate piece of cloth to bound. The means of connection is the needle and the thread. A sewing machine is not changed by this process. It can perform the same task many many times.

Writer: Matt Flynn

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Where: Reference Link Has Evaporated

Date: Mar 10 2013 10:28 AM

What: "The ligase is like a needle and thread. It is responsible for binding the plasmid and gene sticky ends together."

Writer: Kris Hollingsworth

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Where:

Date: Mar 10 2013 10:35 AM

What: As noted in the link, the association with DNA ligase to glue is weak and close to inaccurate. Ligase, itself does not add anything to the ligation reaction. It expedites it, participates in it, but it is not a reactant. This is a basic property of any catalyst, biological or other. "Ligation", the whole process, could be associated with "gluing" a 5-prime to a 3-prime end. But these associations should differentiate between the general process and the particular molecules and involved.

Writer: Janice Creneti

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Where:

Date: Mar 10 2013 10:56 AM

What:

"A DNA strand is like a ladder
They both have rings"

a DNA poem in the link...

Writer: Courtney Ross

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Date: Dec 8 2014 2:46 PM

What:

"Each DNA strand is like a computer that connects with all and receives all. DNA is like a server or a computer that has nodes. A node is a stored memory that is concentrated in the DNA that's like a type of tree that uses cables for connectors of the DNA. The nodes of the DNA trees connect each DNA and can be seen as messengers of all that's occurring. These can be seen symbolically as psychic premonitions or messages of all the events in the DNA strand. This is its computer system "

Writer: HiddenLight777

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Date: Dec 8 2014 2:35 PM

What:

Writer: Not Stated

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Where: Reference Link Has Evaporated

Date: May 28 2015 6:46 PM

What: "The cost of DNA testing is like the cost of the VCR, the cellphone, the PC, the CD player, and the DVD player. Expensive at first, but the price falls. "

Writer: Richard Monday

LCC:

Where: Reference Link Has Evaporated

Date: Mar 10 2013 10:57 AM

What: "Most useful DNA testing is like a peep-hole into your ancestry; your field of view is limited to the direct matrilineal and patrilineal branches of your pedigree.....While DNA Testing is ideal for disproving a suspected relationship, it can only suggest a relationship rather than absolutely prove kinship. DNA won't substitute for traditional research."

Writer: David Bradford

LCC:

Where: Reference Link Has Evaporated

Date: Mar 10 2013 10:59 AM

What: "DNA testing is like the instant replay in sports. In both cases, the strategy is basic: Whatever it takes to make the right decision."

Writer: Not Stated

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Date: Mar 10 2013 11:02 AM

What:

"The DNA polymer is like a very long string of beads which carry the genetic code."

Writer: Gerrard K. H. Teoh

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Where:

Date: Mar 11 2015 11:05 AM

What:

so someone can grab onto it.

Writer: Not Stated

LCC:

Where: Reference Link Has Evaporated

Date: Jan 22 2017 2:37 PM

What:

a pull tab to a zipper. The pull tab helps a person grab onto the slider and move the mechanism on a zipper. The DNA primase creates the RNA primer which is necessary for a DNA polymerase to function.

Writer: Not Stated

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Date: Jan 22 2017 2:57 PM

What: "helicase is like a zipper, making sure the dna strands are open for transcription or replication"

Writer: hayden160

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Date: May 8 2013 10:23 AM

What: 'We learned that the helicase is like our "splitter/unzipper" and our DNA Polymerase is like our "matchmaker"'

Writer: Mr. Koo

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Where: Reference Link Has Evaporated

Date: May 8 2013 10:25 AM

What: "Helicase is like the metal piece that slides along zippers. Once separated, proteins called single-strand DNA-binding proteins will hold the DNA open so the strands don't re-bond.'

Writer: Rene Fester Kratz

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Date: May 8 2013 10:27 AM

What: From page 189 of the linked text. The association is that helicase pushes q dna strand apart like a snowplow pushes the snow apart.

Writer: William A. Dembski

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Date: May 8 2013 10:30 AM

What: "Unzip my Jeans Like a DNA Helicase" The title is highly titillating.

Writer: Bahner/Slick Duo

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Date: May 8 2013 10:32 AM

What: "The arrangement and sequence of the purines and pyrimidines are like notes on pages of music. Their arrangement and sequence determine whether a song,or cacophony of static results" On page 8 of the linked text:

Writer: Janette D. Sherman

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Where:

Date: May 13 2013 7:32 PM

What:

Writer: Me

LCC:

Where: Reference Link Has Evaporated

Date: Mar 26 2014 12:51 PM

What: "The biochemical research is especially haunting. Our entire DNA structure is like a Contact time-release capsule. When we were originally programmed, our basic DNA structure was limited to a double-helix strand. The triggering mechanism that enables us to function as we do is affected by stellar radiation."

Writer: Not Stated

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Date: Mar 10 2013 11:08 AM

What: "The DNA structure is like two spiraling piano keyboards. Any key can be disconnected from the grand piano, obviously changing the tunes that can be played."

Writer: Not Stated

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Date: Mar 10 2013 11:11 AM

What:

"Very rough computer analogy -
DNA replication is like using a computer to copy a file.
DNA synthesis is like using a card punch to originate a file."

Writer: Not Stated

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Where:

Date: Feb 19 2014 3:18 PM

What: Boyce-Jacino compares BioNanomatrix' technology with Google Maps, in which a user can zoom to different levels of detail. "Currently, DNA sequencing is like going house to house on the map. The problem is that you don't know if you're on Elm Street in Ohio or Elm Street in New Jersey. In the genome, because 'Elm Street' might be duplicated, you need to be able to zoom out a little bit and understand where that sequence goes to make sure you know where you are in the genome."

Writer: Michael Boyce-Jacino

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Date: Jul 10 2010 1:49 AM

What: "You need to have a way to fix mistakes., or a proofreading capacity. Each of your cells has 46 DNA moleucles, about 6 billion bases. It only takes a few hours to copy all of this with very few errors. The DNA polymerase is like a word processor. When it sees a mistake it will back up and fix it like hitting the delete key on a computer."

Writer: Ms. Steinhardt

LCC:

Where: Reference Link Has Evaporated

Date: May 6 2013 9:45 AM

What: Yes Indeed. Each square on this chess board can detect the presence or activation of a single gene or series of genes. There is so much information on a single chip that the only way to interpret it is to use computer technology. This is somewhat similar to what astronomers do when when they look at the stars. There are millions and millions and millions of stars and one way to make sense of the pattern is to employ very sophisticated image analysis techniques.

Writer: Lucretia

LCC:

Where: Reference Link Has Evaporated

Date: Apr 29 2013 4:37 PM

What: "A microarray is like a computer microchip, but with DNA molecules instead of circuits. The test uses DNA from a patient's blood. "

Writer: Not Stated

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Date: Apr 29 2013 4:42 PM

What: "DNA polymerase cannot build "random" DNA molecules through the willy-nilly polymerization of nucleotides. It can only make copies of DNA molecules that already exist. Think of it this way -DNA polymerase is like a copy machine, NOT like a type writer, and a copy machine cannot print anything unless it has a template to work with."

Writer: Not Stated

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Date: May 6 2013 9:48 AM

What: "To the contrary, the open binding site of DNA Polymerase is like an available parking spot--anything can drive in [DNA Pol with just a funnel as a binding site, with base pairing positions of template visible at bottom]. There will, however, be constraints on what nucleotides stay in the pocket" The link is a detailed discussion of DNA replication.

Writer: Not Stated

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Date: May 6 2013 9:51 AM

What: "DNA polymerase is like a vehicle that buses in the individual nucleotides. It builds the daughter strand of DNA according to the template set up by the parental strand."

Writer: Not Stated

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Date: May 6 2013 9:53 AM

What:

"If the DNA polymerase is a genetic photocopier, an RNA polymerase is like a genetic fax machine: it produces a copy of the gene for transmission from the cell's nuclear headquarters to its cytoplasmic manufacturing facility."

Fax machines aren't as common as they used to be.

Writer: Gail Dutton, Jeffrey M. Perkel

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Date: Sep 12 2014 11:30 AM

What: "The DNA is like a train track that gets pulled apart by the train."

Writer: Dr. Barry Starr

LCC: QD

Where:

Date: Sep 21 2011 9:01 PM

What: "dna replication is like that game "telephone." one person starts by reciting a sentence to another person #2, in a whisper so no one else can hear. person #2 repeats the sentence to person #3, #3 to #4, and so on. when the final person is told the sentence, he/she says it out loud in order to compare with the original. (of course, all intermediate people get to hear what their sentence turned into.)" The concept alluded to here is mutation. Replication errors can occur and lead to mutations the way a sentence mutates during a game of telephone.

Writer: Not Stated

LCC:

Where: Reference Link Has Evaporated

Date: Feb 12 2012 11:44 AM

What: "Telomeres are like shields and DNA replication is like a battle. Just think about it, what would happen if you were fighting in a battle without a shield? If there is an absence of telomeres, sections of DNA and sections of genes would be gone during replication. "

Writer: Emily Fu-Sum

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Date: Feb 12 2012 11:49 AM

What: DNA hybridization is like a "programmable glue," she said, that can stick cells together because of the highly precise nature of binding between complementary DNA strands: One strand of the DNA helix binds only to its complementary strand and nothing else. By putting a short DNA strand on the surface of one cell and its complementary strand on another cell, the researchers assure that the two lock together exclusively.

Writer: Carolyn Bertozzi

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Date: May 9 2013 6:03 PM

What: "For another lab workhorse, the "gene chip," the problem seems simply to be that it isn't sensitive enough. Gene chips are based on a different, far less sensitive technology than PCR called hybridization. Hybridization is like having 20-20 tunnel vision -- it does great within its limited range, but it can detect absolutely nothing outside it."

Writer: Denise Caruso

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Date: May 9 2013 6:22 PM

What: "In this way, an RNA transcript is like a work order given to the rest of the cell for production of a specific protein." From page 22 of the book: "Review: How to Defeat Your Own Clone and Other Tips for Surviving the Biotech Revolution"

Writer: Kyle Kurpinski

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Date: May 15 2013 1:54 PM

What: "Each primary RNA transcript is like an instruction manual that contains groups of meaningless pages at apparently random intervals. These are called "introns," and must be "snipped" out of the sequence so that the meaningful chapters, called "exons," can be connected to form a final version of the instructions."

Writer: Richard Brill

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Date: May 15 2013 1:56 PM

What: "Transcription is like reading a book, in which letters are codes for a word and a bunch of words can lead to a sentence. In this case, each letter is a nucleotide and each word is a amino acid, which then can be strung along into a sentence or protein."

Writer: Manoj Palavalli

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Where: Reference Link Has Evaporated

Date: May 15 2013 2:02 PM

What: A cartoon comparing the transcription process to a person running through an obstacle course.

Writer: anonymous

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Date: May 15 2013 2:09 PM

What: "Transcription is like having sex. RNA polymerase gets turned on by the DNA, and he's like 'Damn! I want to unzip those genes!' So he gets all on top of her and unwinds her." A piece of an online novel, I think.

Writer: Yuffie

LCC:

Where: Reference Link Has Evaporated

Date: May 15 2013 2:13 PM

What: "Two strands of DNA in the double helix: one is "informational" and the other is the "template". The DNA unwinds and the complementary strand is "transcribed" into RNA... Transcription is like replication: RNA polymerase operating on a DNA strand with RNA nucleotides as the starting materials."

Writer: mfshack

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Date: May 15 2013 2:16 PM

What: "The process of transcription is like making a handwritten copy of a page from the original text for actual use. In this analogy, the cookbook is the DNA. It carries many recipes (for DNA the recipes contain information on how to construct proteins. The recipes are the genes.). The handwritten copy is a transcription of the text (that is, a copy in the same language but in a different form) that is being used for a specific recipe (a certain protein). "

Writer: William Sofer

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Where: Reference Link Has Evaporated

Date: May 15 2013 2:21 PM

What: "DNA amplification is like putting five pieces of paper in a copy machine and asking it to make me one million copies of just those five sheets."

Writer: Melissa Beddow

LCC:

Where: Reference Link Has Evaporated

Date: Jan 1 2014 12:41 PM

What:

"And then I saw the analogy. What if DNA was C++, RNA was C and proteins was machine code? Yes, the hard and dirty work inside the cell was done by the protein code, representing the deep dark actions of the biochemistry, and of course, DNA was the C++. The analogy stretches even further when you think about compiler macros that are often embedded in C++ source files that depend on important information about the enviroment that the program is compiled in. This would make the compiler the ribosome."

Writer: Bosco K. Ho

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Date: Apr 29 2014 6:32 PM

What:

"My technical specialty is DNA fingerprinting, a laboratory procedure that helps us correctly identify and track the DNA samples we process. The results look like a bar code that retail stores use to scan purchases. It serves a similar purpose too. The DNA sequence of any individual is unique. So a DNA fingerprint is like a personalized bar code"

Writer: Joel

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Date: Dec 8 2014 2:52 PM

What:

Writer: Not Stated

LCC:

Where: Reference Link Has Evaporated

Date: Jan 19 2017 4:16 PM

What:

"DNA binding proteins are like your friends after a relationship ends. They keep the single DNA from running back into his ex, and keeps the strand from degradation."

Writer: Not Stated

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Where:

Date: Dec 29 2016 9:33 AM

What: As note just about every where, mammals, human beings can trace their maternal lineage by having their mitochondrial DNA sequenced. This DNA does not cross-over with male DNA and therefore its sequence shows much lower variability than nuclear DNA that has been recombined with paternal DNA. So a comparison of an individuals DNA to other's DNA can give a hint about how closely they may be related, on the mother's lineage.

Writer: LucyG

LCC: QH

Where: Reference Link Has Evaporated

Date: Dec 16 2011 1:15 AM

What:

"Synthetic antiviral drugs have a negative impact on your immune system. They work by interrupting DNA synthesis, and so prevent your cells from making more viruses. Interrupting DNA synthesis is like a double edges sword, because it also inhibits your immune system from making more cells. This leads to a host of side effects. "

Writer: Boyce N. Berkel M.D

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Where:

Date: Feb 19 2014 3:20 PM

What: "There are two types of strands DNA polymerase replicates. There are the leading strands and lagging strands. The leading strand is replicated smoothly, while the lagging strand is like driving down a street with a stop sign every five feet. The lagging strand must be replicated in small single strands, while DNA ligase combines the stand together." The article is a fairly clear and creative description of DNA replication.

Writer: Kelsey

LCC:

Where: Reference Link Has Evaporated

Date: May 9 2013 7:54 PM

What: "That leading strand is like a zipper, it is always replicating. The lagging strand is kind of like lego pieces being connected. Since The leading strand blocks part of the lagging strand, the lagging strand has less nucleotides than a leading strand, making it shorter."

Writer: carney

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Where:

Date: May 9 2013 7:58 PM